Preferred Label : TG-pl-BMP-2 protein, recombinant;
MeSH note : a form of BMP-2 engineered for incorporation into fibrin cell ingrowth matrices for
bone repair; contains an N-terminal transglutaminase substrate (TG) domain provides
covalent attachment to fibrin during coagulation under the influence of the blood
transglutaminase factor XIIIa, a central plasmin substrate (pl) domain provides a
cleavage site for local release of the attached growth factor from the fibrin matrix
under the influence of cell-activated plasmin & a C-terminal human BMP-2 domain provides
osteogenic activity;
MeSH synonym : TG-pl-BMP-2 recombinant protein;
Is substance : O;
Origin ID : C502387;
UMLS CUI : C1571346;
MeSH term(s) associated for indexing
- Record concept(s)
- Semantic type(s)
