4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one

Preferred Label : 4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one;

MeSH note : multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma;

CISMeF synonym : CHIR 258; TKI 258; dovitinib;

MeSH hyponym : TKI258; TKI-258; CHIR258; CHIR-258;

Is substance : O;

Details

Origin ID

C500007;

UMLS CUI

C2000847;

Automatic exact mappings (from CISMeF team)
- Dovitinib [NCIt concept]
MeSH term(s) associated for indexing
- benzimidazoles [MeSH Descriptor]
- quinolones [MeSH Descriptor]
Record concept(s)
- 4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one [MeSH concept]
- CHIR 258 [MeSH concept]
- TKI 258 [MeSH concept]
- dovitinib [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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