Preferred Label : neprilysin 2, rat;
MeSH note : a metalloprotease that belongs to the M-13 sub-family of zinc-dependent metallopeptidases;
almost exclusively expressed in selected neuronal populations of the brain and spinal
cord; the only exceptions were the intermediate and anterior lobes of the pituitary
as well as the choroid plexuses, where NEP2 was also strongly expressed; these localisations
as well as those in the hypothalamic nuclei, together with the previously established
pattern of cleaved peptides, suggest the involvement of NEP2 in the metabolism of
neurohormones of the hypothalamo-pituitary axis; has been sequenced;
MeSH synonym : NEP2 protein, rat;
Registry Number MeSH : EC 3.4.24.11;
Is substance : O;
UNII : EC 3.4.24.11;
Origin ID : C476216;
UMLS CUI : C1260198;
MeSH term(s) associated for indexing
- Record concept(s)
- Semantic type(s)
