presenilinase, human

Preferred Label : presenilinase, human;

MeSH note : presenilin undergoes endoproteolysis by presenilinase to generate the functional N-terminal and C-terminal fragment heterodimers (NTF/CTF) that may harbor the gamma-secretase active site; presenilinase has characteristics of an aspartyl protease, but this activity is distinct from gamma-secretase;

Registry Number MeSH : EC 3.4.23.-;

Is substance : O;

Details

Origin ID

C475285;

UMLS CUI

C1259394;

Automatic exact mappings (from CISMeF team)
- Presenilin-1 [NCIt concept]
- Presenilin-2 [NCIt concept]
MeSH term(s) associated for indexing
- aspartic acid endopeptidases [MeSH Descriptor]
Record concept(s)
- presenilinase, human [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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