TTL-ETV6 fusion protein, human

Preferred Label : TTL-ETV6 fusion protein, human;

MeSH note : a fusion gene in acute lymphoblastic leukemia & involved in leukemogenesis; In leukemic cells both reciprocal fusion transcripts, ETV6/TTL and TTL/ETV6, were expressed; the predominant fusion transcript, TTL/ETV6 encodes a predicted 530 aa fusion protein containing 89 aa of the N-terminal TTL fusing to the helix-loop-helix domain and ETS-binding domain of ETV6;

CISMeF synonym : ETV6-TTL fusion protein, human;

MeSH synonym : TTL-ETV6 protein, human;

Related MeSH term : ETV6-TTL protein, human;

Is substance : O;

Details

Origin ID

C475279;

UMLS CUI

C1259386;

MeSH term(s) associated for indexing
- ETS Translocation Variant 6 Protein [MeSH Descriptor]
- oncogene proteins, fusion [MeSH Descriptor]
Record concept(s)
- ETV6-TTL fusion protein, human [MeSH concept]
- TTL-ETV6 fusion protein, human [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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