pretomanid - CISMeF

Preferred Label : pretomanid;

MeSH note : nitroimidazopyran derived from 5-nitroimidazoles; a prodrug that requires activation by a bacterial F420-depedent glucose-6-phosphate dehydrogenase (Fgd) and nitroreductase to activate components that then inhibit bacterial mycolic acid and protein synthesis; structure in first source;

CISMeF synonym : PA824; PA 824;

MeSH synonym : 2-nitro-6-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine;

MeSH hyponym : PA824 cpd; PA-824;

Is substance : O;

Details

Origin ID

C410767;

UMLS CUI

C4310440;

ATC code(s)
- pretomanid [ATC Code]
Currated CISMeF NLP mapping
- Pretomanid [LOINC component]
- Pretomanid [NCIt concept]
- Pretomanid [SMS substance]
- Pretomanid (substance) [SNOMED CT concept]
MeSH indexing information
- antitubercular agents [MeSH Descriptor]
MeSH term(s) associated for indexing
- nitroimidazoles [MeSH Descriptor]
Record concept(s)
- PA 824 [MeSH concept]
- pretomanid [MeSH concept]
See also inter- (CISMeF)
- Product containing pretomanid (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Pretomanid [LOINC component]
- Pretomanid [NCIt concept]
- Pretomanid (substance) [SNOMED CT concept]
- Product containing pretomanid (medicinal product) [SNOMED CT concept]
- pretomanid [ATC Code]
Validated automatic mappings to BTNT
- pretomanid [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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