insulin-cleaving membrane proteinase

Preferred Label : insulin-cleaving membrane proteinase;

MeSH note : membrane proteinase from Pseudomonas aeruginosa cleaves Glu(13)-Ala(14) and Tyr(16)-Leu(17) of insulin B-chain; Phe(25)-Tyr(26) and His(10)-Leu(11) are secondary cleavage sites; partial amino acid sequence in first source;

MeSH synonym : ICMP enzyme;

Registry Number MeSH : EC 3.4.24.-;

Is substance : O;

Details

Origin ID

C121424;

UMLS CUI

C0909044;

Automatic exact mappings (from CISMeF team)
- Disintegrin and Metalloproteinase Domain-Containing Protein 15 [NCIt concept]
- Disintegrin and Metalloproteinase Domain-Containing Protein 8 [NCIt concept]
MeSH term(s) associated for indexing
- metalloendopeptidases [MeSH Descriptor]
Record concept(s)
- insulin-cleaving membrane proteinase [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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