Preferred Label : VAB-8 protein, C elegans;
MeSH note : vab-8 gene encodes a novel protein containing an atypical kinesin-like motor domain
that is required for many posteriorly-directed cell migrations, as well as axonal
outgrowth and pathfinding; vab-8 encodes two protein isoforms: VAB-8S, a novel protein
expressed in migrating cells, and VAB-8L, which contains a kinesin-related domain,
is expressed in neurons and functions in growth cone migrations; VAB-8 interacts with
UNC-51, a serine-threonine kinase also required for axon outgrowth; isolated from
Caenorhabditis elegans; amino acid sequence in first source;
MeSH synonym : klp-5 protein, C elegans; unc-107 protein, C elegans;
Is substance : O;
Origin ID : C112201;
UMLS CUI : C1257354;
MeSH term(s) associated for indexing
- Record concept(s)
- Semantic type(s)
