Preferred Label : sitaxsentan;
MeSH note : endothelin A receptor antagonist; structure in first source;
CISMeF synonym : TBC-11251;
MeSH synonym : N-(4-chloro-3-methyl-5-isoxazolyl)-2-(3,4-(methylenedioxy)-6-methyl)phenylacetyl-3-thiophenesulfonamide; N-(4-chloro-3-methyl-5-isoxazolyl)-2-((4,5-(methylenedioxy)-O-toly)acetyl)-3-thiophenesulfonamide;
MeSH hyponym : TBC 11251; TBC11251;
Is substance : O;
UNII : J9QH779MEM;
Origin ID : C106276;
UMLS CUI : C1704271;
ATC code(s)
ATC code(s)
Currated CISMeF NLP mapping
Manual BTNT mappings - CISMeF
MeSH indexing information
MeSH term(s) associated for indexing
Pharmacological action(s)
Record concept(s)
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
https://www.ema.europa.eu/medicines/human/EPAR/Thelin
2011
false
United Kingdom
French
English
syndication feed
Endothelin A Receptor Antagonists
Endothelin A Receptor Antagonists
hypertension, pulmonary
adult
drug interactions
treatment outcome
drug evaluation
isoxazoles
thiophenes
sitaxentan
sitaxsentan
orphan drug production
sitaxsentan
isoxazoles
thiophenes
drug evaluation
summary of product characteristics
package leaflet
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https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/16113a-fra.php
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14627a-fra.php
2010
Canada
French
English
sitaxsentan
orphan drug production
Safety-Based drug withdrawals
hypertension, pulmonary
administration, oral
sitaxentan
thiophenes
isoxazoles
receptors, endothelin
liver diseases
isoxazoles
thiophenes
pharmacovigilance note
patient education handout
---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Thelin_January-30-2008_fr.pdf
2008
Canada
French
canada
canada
insurance, health, reimbursement
insurance, health, reimbursement
hypertension, pulmonary
hypertension, pulmonary
isoxazoles
isoxazoles
thiophenes
thiophenes
receptors, endothelin
receptors, endothelin
sitaxsentan
sitaxsentan
sitaxentan
sitaxentan
isoxazoles
isoxazoles
thiophenes
thiophenes
drug evaluation
drug evaluation
---
http://www.has-sante.fr/display.jsp?id=c_560668
http://www.has-sante.fr/upload/docs/application/pdf/ct-4468_thelin_.pdf
http://www.has-sante.fr/upload/docs/application/pdf/2010-04/thelin_ct_4468.pdf
2007
France
French
administration, oral
orphan drug production
sitaxsentan
isoxazoles
thiophenes
sitaxentan
hypertension, pulmonary
treatment outcome
tablets
isoxazoles
thiophenes
evaluation of the transparency committee
---