Preferred Label : FK506 macrolide 9-hydroxylase, streptomyces;
MeSH note : catalyzes hydroxylation at position C-9 of the FK506 and FK520 macrolactone ring;
isolated from Streptomyces; FK506 and FK520 are 23-membered macrocyclic polyketides
with potent immunosuppressive and antifungal activities;
MeSH synonym : cytochrome P-450 9-deoxo-FK506 hydroxylase, Streptomyces; FkbD protein, Streptomyces; FK520 macrolide 9-hydroxylase, Streptomyces;
Registry Number MeSH : EC 1.14.-;
Is substance : O;
Origin ID : C101653;
UMLS CUI : C1430437;
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