efavirenz - CISMeF

Preferred Label : efavirenz;

MeSH note : HIV-1 reverse transcriptase inhibitor; RN given for ( -)-isomer; L-743,726 is the (S)-isomer; structure in first source;

CISMeF synonym : 6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one; DMP 266; L 743726; stocrin; sustiva; Bristol-Myers squibb brand of efavirenz; du pont brand of efavirenz; merck sharp & dohme brand of efavirenz; united drug brand of efavirenz;

MeSH synonym : efavirenz, (S)-isomer; (s)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one;

MeSH hyponym : DMP-266; L-743726; L 743,726; L-743,726;

MeSH Related Number : efavirenz, (R)-isomer; efavirenz, (S)-isomer; 154635-17-3 (efavirenz); CEE19E5D5F;

Registry Number MeSH : 154635-17-3;

Related CAS MeSH : 154801-74-8 (efavirenz, (R)-isomer); 154598-52-4 (efavirenz, (S)-isomer);

related registry number list (CISMeF) : 154598-52-4 ((S)-isomer); 154801-74-8 ((R)-isomer);

Is substance : O;

UNII : JE6H2O27P8;

InChIKey : XPOQHMRABVBWPR-ZDUSSCGKSA-N;

Details

Origin ID

C098320;

UMLS CUI

C0674428;

ATC code(s)
- emtricitabine, tenofovir disoproxil and efavirenz [ATC Code]
ATC code(s)
- efavirenz [ATC Code]
- lamivudine, tenofovir disoproxil and efavirenz [ATC Code]
Currated CISMeF NLP mapping
- Efavirenz [LOINC component]
- Efavirenz [SMS substance]
- Efavirenz [ICD-11 Extension code]
- Efavirenz [NCIt concept]
- Efavirenz (substance) [SNOMED CT concept]
MeSH term(s) associated for indexing
- alkynes [MeSH Descriptor]
- benzoxazines [MeSH Descriptor]
- cyclopropanes [MeSH Descriptor]
Pharmacological action(s)
- Cytochrome P-450 CYP2B6 Inducers [MeSH Descriptor]
- Cytochrome P-450 CYP2C19 Inhibitors [MeSH Descriptor]
- Cytochrome P-450 CYP2C9 Inhibitors [MeSH Descriptor]
- Cytochrome P-450 CYP3A Inducers [MeSH Descriptor]
- reverse transcriptase inhibitors [MeSH Descriptor]
Record concept(s)
- DMP 266 [MeSH concept]
- L 743726 [MeSH concept]
- efavirenz [MeSH concept]
- efavirenz, (R)-isomer [MeSH concept]
- stocrin [MeSH concept]
- sustiva [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Efavirenz [LOINC component]
- Efavirenz [NCIt concept]
- Efavirenz (substance) [SNOMED CT concept]
- Product containing efavirenz (medicinal product) [SNOMED CT concept]
- efavirenz [ATC Code]
Validated automatic mappings to BTNT
- efavirenz [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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