MHC class II transactivator protein

Preferred Label : MHC class II transactivator protein;

MeSH note : a major histocompatibility complex class II transactivator; essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter; defects in MHC2TA are a cause of BARE LYMPHOCYTE SYNDROME type II (BLS II), a severe form of SCID; RefSeq NM_000246 (human); NM_007575 (mouse);

CISMeF synonym : C2ta protein, mouse; MHC2TA protein, human; Mhc2ta protein, rat;

MeSH synonym : class II transactivator;

MeSH hyponym : MHC class II transactivator protein, human; CIITA protein, human; C2TA protein, human; class II transactivator protein, mouse; CIITA protein, mouse;

Is substance : O;

Details

Origin ID

C083728;

UMLS CUI

C0247848;

Automatic exact mappings (from CISMeF team)
- Class II major histocompatibility complex transactivator [OMIM gene]
- MHC Class II Transactivator [NCIt concept]
MeSH indexing information
- genes, MHC class II [MeSH Descriptor]
MeSH term(s) associated for indexing
- nuclear proteins [MeSH Descriptor]
- trans-activators [MeSH Descriptor]
Record concept(s)
- C2ta protein, mouse [MeSH concept]
- MHC class II transactivator protein [MeSH concept]
- MHC2TA protein, human [MeSH concept]
- Mhc2ta protein, rat [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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