5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate

Preferred Label : 5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate;

MeSH note : inhibits the production of full-length minus strand DNA in an endogenous reverse transcriptase reaction; is also used as a chain terminator substrate; RN refers to (2R-cis)-isomer;

MeSH synonym : FTCTP;

MeSH Related Number : 5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate, (2S-cis)-isomer; 145919-60-4 ((2S-cis)-isomer);

Registry Number MeSH : 145819-92-7;

Related CAS MeSH : 145919-60-4 (5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate, (2S-cis)-isomer);

related registry number list (CISMeF) : 145919-60-4 ((2S-cis)-isomer);

Is substance : O;

Details

Origin ID

C083567;

UMLS CUI

C0661643;

MeSH indexing information
- HIV reverse transcriptase [MeSH Descriptor]
MeSH term(s) associated for indexing
- cytidine triphosphate [MeSH Descriptor]
- thiophenes [MeSH Descriptor]
Record concept(s)
- 5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate [MeSH concept]
- 5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate, (2S-cis)-isomer [MeSH concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients