geranylgeranyltransferase type-I

Preferred Label : geranylgeranyltransferase type-I;

MeSH note : involved in protein isoprenylation; transfers geranylgeranyl group to Cys fourth from the C-terminal of GTP-binding proteins; see also Rab, ras, and rhoA p21 geranylgeranyl- transferases and component A, Rab geranylgeranyltransferase; RefSeq NM_172627 (mouse); NM_031082 (rat); NM_005023 (human);

CISMeF synonym : PGGT1B protein, human; Pggt1b protein, mouse; Pggt1b protein, rat;

MeSH synonym : GGTase-I; geranylgeranyltransferase ras protein; GGTase I; protein geranylgeranyltransferase; geranylgeranyltransferase I; ras protein GG transferase; protein GGTase; geranylgeranyl-protein transferase type 1; ras protein geranylgeranyltransferase; CAAX geranylgeranyl transferase;

MeSH hyponym : protein geranylgeranyltransferase type I, beta subunit, mouse; protein geranylgeranyltransferase type I, beta subunit, human; protein geranylgeranyltransferase type I, beta subunit, rat;

Registry Number MeSH : EC 2.5.1.-;

Is substance : O;

Details

Origin ID

C083291;

UMLS CUI

C0138843;

Currated CISMeF NLP mapping
- Geranylgeranyl Transferase [NCIt concept]
MeSH indexing information
- diterpenes [MeSH Descriptor]
- protein prenylation [MeSH Descriptor]
MeSH term(s) associated for indexing
- alkyl and aryl transferases [MeSH Descriptor]
Record concept(s)
- PGGT1B protein, human [MeSH concept]
- Pggt1b protein, mouse [MeSH concept]
- Pggt1b protein, rat [MeSH concept]
- geranylgeranyltransferase type-I [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Geranylgeranyl Transferase [NCIt concept]

Keyword's position in hierarchy(ies) :

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