protein prenylation

Preferred Label : protein prenylation;

MeSH definition : A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl diphosphate or geranylgeranyl diphosphate, are derived from the same biochemical pathway that produces cholesterol.;

MeSH synonym : prenylation, protein;

MeSH hyponym : protein farnesylation; protein polyisoprenylation; protein isoprenylation; protein geranylgeranylation; Polyisoprenylation, Protein; Post-Translational Isoprenylation; Farnesylation, Protein; Geranylgeranylation, Protein;

Wikipedia link : https://en.wikipedia.org/wiki/Protein isoprenylation;

Details

Origin ID

D017368;

UMLS CUI

C0162766;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- ethics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- protein farnesylation [GO term]
- protein geranylgeranylation [GO term]
CISMeF manual mappings
- Protein prenylation [OMIConto structure]
Currated CISMeF NLP mapping
- protein prenylation [GO term]
Indexing information
- BZA 5B [MeSH Supplementary Concept]
- CHM protein, human [MeSH Supplementary Concept]
- N-(4-(1-cyclohexyl-3-ethylthioprop-2-ylaminomethyl)-2-(2-methylphenyl)benzoyl)methionine [MeSH Supplementary Concept]
- geranylgeranyltransferase type-I [MeSH Supplementary Concept]
- p21(ras) farnesyl-protein transferase [MeSH Supplementary Concept]
- ptb1 protein, S pombe [MeSH Supplementary Concept]
Record concept(s)
- protein farnesylation [MeSH concept]
- protein geranylgeranylation [MeSH concept]
- protein isoprenylation [MeSH concept]
- protein polyisoprenylation [MeSH concept]
- protein prenylation [MeSH concept]
Semantic type(s)
- Molecular Function [UMLS semantic type]
UMLS correspondences (same concept)
- Protein prenylation [OMIConto structure]
- obsolete C-terminal protein prenylation [GO term]
- protein prenylation [GO term]

Keyword's position in hierarchy(ies) :

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