poly(A)-specific ribonuclease

Preferred Label : poly(A)-specific ribonuclease;

MeSH note : bifunctional enzyme responsible for both poly(A)-polymerizing & poly(A)-hydrolyzing activities; removes the poly(A) tail as the first step in degrading mRNA; RefSeq NM_002582 (human);

CISMeF synonym : parn-A protein, xenopus; PARN protein, human; PAN2 protein, S cerevisiae; PARN protein, arabidopsis;

MeSH synonym : poly(A) nuclease; mRNA poly(A) nuclease; poly(A)ribonuclease; poly(A) ribonuclease (PAN); PARN1 protein, C elegans;

MeSH hyponym : xPARN protein, Xenopus; poly(A)-specific ribonuclease, Xenopus; deadenylation nuclease, human; poly(A)-specific ribonuclease, human; YGL094C protein, S cerevisiae; AHG2 protein, Arabidopsis; poly(A) ribonuclease , Arabidopsis;

Registry Number MeSH : EC 3.1.13.4;

Is substance : O;

UNII : EC 3.1.13.4;

Details

Origin ID

C062401;

UMLS CUI

C0071388;

Automatic exact mappings (from CISMeF team)
- Poly(A)-Specific Ribonuclease PARN [NCIt concept]
- Poly(A)-specific ribonuclease (substance) [SNOMED CT concept]
- Polyadenylate-specific ribonuclease [OMIM gene]
- Protein-Lysine 6-Oxidase [NCIt concept]
- poly(A)-specific ribonuclease [ORDO Gene]
- poly(A)-specific ribonuclease [HGNC gene]
- poly(a)-specific ribonuclease [SNOMED Notion]
MeSH indexing information
- arabidopsis proteins [MeSH Descriptor]
- saccharomyces cerevisiae proteins [MeSH Descriptor]
- xenopus proteins [MeSH Descriptor]
MeSH term(s) associated for indexing
- exoribonucleases [MeSH Descriptor]
Record concept(s)
- PAN2 protein, S cerevisiae [MeSH concept]
- PARN protein, arabidopsis [MeSH concept]
- PARN protein, human [MeSH concept]
- parn-A protein, xenopus [MeSH concept]
- poly(A)-specific ribonuclease [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Poly(A)-specific ribonuclease (substance) [SNOMED CT concept]
- poly(a)-specific ribonuclease [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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