fibrolase - CISMeF

Preferred Label : fibrolase;

MeSH note : from the venom of Agkistrodon contortrix; direct-acting fibrin-degrading zinc-metalloproteinase; MW 23-25kDa; cleaves primarily the Aa-chain of human fibrinogen & fibrin between the Lys-413 & Leu-414 position; the Bb chain is cleaved more slowly; gamma chain is minimally affected;

MeSH synonym : Agkistrodon contortrix fibrin-degrading metalloprotease;

Registry Number MeSH : EC 3.4.24.-;

Is substance : O;

Details

Origin ID

C058789;

UMLS CUI

C0060374;

Automatic exact mappings (from CISMeF team)
- Disintegrin and Metalloproteinase Domain-Containing Protein 15 [NCIt concept]
- Disintegrin and Metalloproteinase Domain-Containing Protein 8 [NCIt concept]
- Fibrolase (substance) [SNOMED CT concept]
MeSH term(s) associated for indexing
- metalloendopeptidases [MeSH Descriptor]
Record concept(s)
- fibrolase [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Fibrolase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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