Preferred Label : retinoid isomerohydrolase;

MeSH note : catalyzes the isomerization of all trans-retinol to 11-cis-retinol in the dark; found in the pigment epithelium in the eye; also converts all-trans-retinyl esters to 11-cis-retinol;

CISMeF synonym : RPE65 protein, human; RPE65c protein, zebrafish; Rpe65 protein, mouse; Rpe65 protein, rat;

MeSH synonym : retinoid isomerase; retinol isomerase;

MeSH hyponym : 13-cis isomerohydrolase, zebrafish; retinal pigment epithelium-specific protein 65c protein, zebrafish; RPE65 protein, zebrafish; retinal pigment epithelium specific 65 kDa protein, zebrafish; retinal pigment epithelium 65 protein, rat; retinal pigment epithelium-specific protein, human; retinal pigment epithelium 65 protein, human; retinal pigment epithelium 65 protein, mouse;

MeSH Related Number : CH2LY7Q64L;

Registry Number MeSH : EC 5.2.1.7; EC 3.1.1.64;

Is substance : O;

UNII : EC 3.1.1.64;

Details


Main resources

You can consult :


https://www.has-sante.fr/portail/jcms/c_2964759/fr/luxturna
https://www.has-sante.fr/portail/jcms/c_2964759/fr/luxturna-voretigene-neparvovec-therapie-genique
2019
false
true
false
false
France
French
treatment outcome
adult
child
orphan drug production
retinoid isomerohydrolase
retinoid isomerohydrolase
retinal dystrophies
retinal dystrophies
genetic therapy
injections
evaluation of the transparency committee
Voretigene Neparvovec
guidelines for drug use
cis-trans-isomerases
voretigene neparvovec
Hereditary Retinal Dystrophy
cis-trans-isomerases
cis-trans-isomerases

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https://www.ema.europa.eu/en/medicines/human/EPAR/luxturna
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
adult
child
orphan drug production
retinoid isomerohydrolase
retinoid isomerohydrolase
retinal dystrophies
retinal dystrophies
genetic therapy
injections
product surveillance, postmarketing
pregnancy
breast feeding
drug evaluation, preclinical
voretigene neparvovec
Hereditary Retinal Dystrophy
Voretigene Neparvovec
Voretigene Neparvovec
cis-trans-isomerases
cis-trans-isomerases

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03/05/2025


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