Preferred Label : rotigotine;

MeSH note : dopamine receptor agonist; structure given in first source; RN given refers to cpd without isomeric designation;

CISMeF synonym : 2-(N-n-propyl-N-2-thienylethylamino)-5-hydroxytetralin; N 0923; N 0924; neupro; rotigotine CDS; N 0437; rotigotine, ( --)-;

MeSH hyponym : ( )-5,6,7,8-tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol; N-0437; racemic N-0437; rotigotine ( -)-form; 1-naphthalenol, 5,6,7,8-tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-; ( --)-5,6,7,8-tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol;

Related MeSH term : N-0923; N-0924;

MeSH Related Number : N 0437, hydrochloride, (R)-isomer; N 0437, ( -)-isomer; N 0437, (-)-isomer; N 0437, (R)-isomer; N 0437, hydrochloride, (S)-isomer; 112835-48-0 ((R)-isomer); 113349-24-9 (( -)-isomer); 125572-92-1 (HCl(R)-isomer); 125572-93-2 (HCl(S)-isomer); 99755-59-6 ((-)-isomer); 112835-48-0 (N 0437, hydrochloride, (R)-isomer); 113349-24-9 (N 0437, ( -)-isomer); 125572-92-1 (N 0437, hydrochloride, (R)-isomer); 125572-93-2 (N 0437, hydrochloride, (S)-isomer); 99755-59-6 (N 0437, (-)-isomer); 5QTR54Z0E1; N8FO6Z42IR;

Registry Number MeSH : 92206-54-7; 5QTR54Z0E1;

Related CAS MeSH : 113349-24-9 (N 0437, ( -)-isomer); 99755-59-6 (N 0437, (-)-isomer); 112835-48-0 (N 0437, (R)-isomer); 125572-93-2 (N 0437, hydrochloride, (S)-isomer); 125572-92-1 (N 0437, hydrochloride, (R)-isomer);

related registry number list (CISMeF) : 112835-48-0 ((R)-isomer); 113349-24-9 (( -)-isomer); 125572-92-1 (HCl(R)-isomer); 125572-93-2 (HCl(S)-isomer); 99755-59-6 ((-)-isomer);

CISMeF hyponym : Neupro;

Is substance : O;

UNII : 87T4T8BO2E;

Details


Main resources

You can consult :


http://www.has-sante.fr/portail/jcms/c_1736412/fr/quelle-place-pour-les-agonistes-dopaminergiques-dans-le-syndrome-des-jambes-sans-repos-fiche-bum
2014
true
France
French
restless legs syndrome
administration, oral
pramipexole
dopamine agonists
guidelines for drug use
administration, cutaneous
transdermal patch
dopamine agonists
rotigotine
restless legs syndrome
signs and symptoms
Dietary and nutritional issues
health behavior
ropinirole
ropinirole
ropinirole hydrochloride
ropinirole hydrochloride
ropinirole
treatment outcome
severity of illness index
algorithms
indoles
indoles
benzothiazoles
benzothiazoles
rotigotine
rotigotine
Pramipexole
Pramipexole

---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailTwo.php?lang=fr&linkID=SBD00233
2013
false
false
false
Canada
Rotigotine 2mg/24hours transdermal patch (product)
Rotigotine 4mg/24hours transdermal patch (product)
Rotigotine 6mg/24hours transdermal patch (product)
Product containing rotigotine (medicinal product)
rotigotine
drug information
Neupro
rotigotine
tetrahydronaphthalenes
thiophenes

---
http://www.has-sante.fr/portail/jcms/c_1648987/fr/neupro
http://www.has-sante.fr/portail/jcms/c_1648986/fr/neupro-18092013-avis-ct12799
2013
false
France
French
guidelines for drug use
evaluation of the transparency committee
treatment outcome
insurance, health, reimbursement
transdermal patch
administration, cutaneous
rotigotine
restless legs syndrome
rotigotine
adult
tetrahydronaphthalenes
tetrahydronaphthalenes
thiophenes
thiophenes

---
https://www.ema.europa.eu/medicines/human/EPAR/Neupro
2012
false
United Kingdom
English
French
syndication feed
rotigotine
parkinson disease
treatment outcome
administration, cutaneous
pregnancy
breast feeding
rotigotine
rotigotine
tetrahydronaphthalenes
thiophenes
dopamine agonists
dopamine agonists
tetrahydronaphthalenes
thiophenes
drug evaluation
package leaflet
summary of product characteristics
restless legs syndrome

---
https://www.ema.europa.eu/medicines/human/EPAR/Leganto
2012
false
United Kingdom
French
English
summary of product characteristics
package leaflet
syndication feed
drug approval
rotigotine
rotigotine
tetrahydronaphthalenes
tetrahydronaphthalenes
thiophenes
thiophenes
dopamine agonists
dopamine agonists
transdermal patch
administration, cutaneous
restless legs syndrome
adult
drug interactions
pregnancy
breast feeding
rotigotine
drug evaluation, preclinical
parkinson disease
drug therapy, combination

---
https://www.cadth.ca/sites/default/files/pdf/E0056_Rotigotine-Patch-Parkinsons-Disease_cetap_f.pdf
https://www.cadth.ca/sites/default/files/pdf/E0056_Rotigotine-Patch-Parkinsons-Disease_cetap_e.pdf
2008
Canada
English
French
thiophenes
tetrahydronaphthalenes
dopamine agonists
parkinson disease
thiophenes
tetrahydronaphthalenes
dopamine agonists
administration, cutaneous
antiparkinson agents
antiparkinson agents
randomized controlled trials as topic
antiparkinson agents
thiophenes
tetrahydronaphthalenes
dopamine agonists
united states
canada
treatment outcome
rotigotine
rotigotine
rotigotine
rotigotine
rotigotine
rotigotine
rotigotine
drug evaluation

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17/05/2024


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