Preferred Label : DNA reverse gyrase;
MeSH note : An atypical topoisomerase found in hyperthermophilic microorganisms, such as archaea
and hyperthermophilic eubacteria. Reverse gyrase is able to positively supercoil DNA
in the presence of ATP as helicases. In recent literature, it is classified as one
of the Type I DNA topoisomerases (including topoisomerase I, III, V, and reverse gyrase).
Previously, this enzyme was indexed under DNA Topoisomerase (ATP-Hydrolysing), a Type
II DNA topoisomerase.;
MeSH synonym : reverse gyrase;
Registry Number MeSH : EC 5.99.1.-;
Is substance : O;
Origin ID : C041813;
UMLS CUI : C0058597;
MeSH term(s) associated for indexing
Record concept(s)
Semantic type(s)