Preferred Label : peptidylglycine monooxygenase;
MeSH note : forms alpha-amide from C-terminal glycine precursor of peptide hormones by oxidation
of hydrogen & spontaneous hydrolysis of resulting imino linkage; posseses both an
alpha-hydroxylation domain (PHM) and an alpha-amidation domain (PAL); PAM refers to
the bifunctional enzyme; may be the same as bovine Somatotropin; RefSeq NM_013626
(mouse), NM_013000 (rat), NM_138822 (human);
CISMeF synonym : SP-GLYE protein, human; alpha-amidation monooxygenase; substance P-Gly12 protein, human;
MeSH synonym : peptidylglycine alpha-amidating monooxygenase; peptidylglycine hydroxylase; peptidylglycine alpha-hydroxylating monooxygenase; peptidyl alpha-amidating monooxygenase; peptidylglycine 2-hydroxylase; alpha-amidating enzyme AE-II; peptidyl-glycine alpha-amidating monooxygenase;
MeSH hyponym : peptidylglycine alpha-amidating monooxygenase, mouse; peptide C-terminal alpha-amidating enzyme II, Xenopus; peptidylglycine alpha-amidating monooxygenase, rat;
MeSH Related Number : pam protein, mouse; AE-II protein, xenopus; pam protein, rat;
Registry Number MeSH : EC 1.14.17.3;
Related CAS MeSH : EC 1.14.17.3 (Pam protein, mouse); EC 1.14.17.3 (AE-II protein, xenopus); EC 1.14.17.3 (Pam protein, rat);
related registry number list (CISMeF) : EC 1.14.17.3;
Is substance : O;
UNII : EC 1.14.17.3;
Origin ID : C035189;
UMLS CUI : C0136072;
MeSH indexing information
- MeSH term(s) associated for indexing
- Record concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
