Preferred Label : diacerein;
MeSH note : chelates with bivalent metals; a quinone which possesses redox properties; metabolized
to active rhein; proposed mechanisms include inhibiting IL1 and metalloproteinases;
called a slow acting symptomatic drug in osteoarthritis; no effect of cyclooxygenase;;
CISMeF synonym : art brand of diacetylrhein; zondar; negma brand of diacetylrhein; niverpharm brand of diacetylrhein;
MeSH synonym : diacetyl-rhein; diacerhein; 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid; 4,5-diacetoxyanthraquinone-2-carboxylic acid; 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroic acid, diacetate; 2-anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-; diacetylrhein; 1,8-diacetoxy-3-carboxyanthraquinone; rhein diacetate;
MeSH hyponym : SF277; AC-203; M-01AX21;
MeSH CAS label : 2-Anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-;
MeSH Related Number : 13739-02-1;
Registry Number MeSH : 13739-02-1;
Codes EINECS : 237-310-2;
Is substance : O;
UNII : 4HU6J11EL5;
InChIKey : TYNLGDBUJLVSMA-UHFFFAOYSA-N;
Origin ID : C025292;
UMLS CUI : C0057678;
ATC code(s)
CISMeF manual mappings
MeSH term(s) associated for indexing
Pharmacological action(s)
Record concept(s)
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
http://www.cochrane.org/fr/CD005117
2014
false
true
false
United Kingdom
France
anthraquinones
meta-analysis
french abstract
diacerein
osteoarthritis
---
http://www.has-sante.fr/portail/jcms/c_724621/zondar
http://www.has-sante.fr/portail/jcms/c_1356140/zondar
http://www.has-sante.fr/portail/jcms/c_1356790/fr/zondar-09012013-avis-ct12262
2013
France
French
osteoarthritis, knee
osteoarthritis, hip
adult
administration, oral
diacerein
anti-inflammatory agents
diacerein
treatment outcome
anthraquinones
evaluation of the transparency committee
insurance, health, reimbursement
---
http://www.has-sante.fr/portail/jcms/c_1356138/art-50
http://www.has-sante.fr/portail/upload/docs/application/pdf/2013-02/art50_ri2012_avis2modifie17jan2013_ct12263.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_400762
2013
France
French
administration, oral
diacerein
anthraquinones
insurance, health, reimbursement
adult
anti-inflammatory agents
diacerein
anthraquinones
guidelines for drug use
evaluation of the transparency committee
osteoarthritis, knee
osteoarthritis, hip
treatment outcome
randomized controlled trials as topic
meta-analysis as topic
pain
pain measurement
---
http://www.has-sante.fr/portail/jcms/c_1621213/fr/art-50-/-zondar-chondrosulf-et-piascledine-service-medical-rendu-insuffisant-dans-le-traitement-de-larthrose
2013
true
France
French
diacerein
administration, oral
treatment outcome
diacerein
insurance, health, reimbursement
chondroitin sulfates
Chondroitin Sulfate, Sodium Salt
chondroitin sulfate
pain
piascledine
avocado and soyabean oil, unsaponifiables
soybean oil
persea
osteoarthritis, knee
osteoarthritis, hip
evaluation of the transparency committee
phytosterols
plant extracts
vitamin E
drug combinations
anthraquinones
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66943247
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63641749
2012
France
summary of product characteristics
package leaflet
diacerein
capsules
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66676958
2012
France
summary of product characteristics
package leaflet
diacerein
capsules
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69633912
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64598083
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63008327
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64803339
2012
France
summary of product characteristics
package leaflet
diacerein
capsules
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62117512
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66262213
2012
France
summary of product characteristics
package leaflet
diacerein
capsules
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64847086
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61055278
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67732819
2012
France
summary of product characteristics
package leaflet
diacerein
capsules
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69977660
2012
France
summary of product characteristics
package leaflet
diacerein
capsules
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60097242
2012
France
summary of product characteristics
package leaflet
diacerein
capsules
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60756618
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63830486
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67936106
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69070563
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65524730
2012
France
summary of product characteristics
package leaflet
capsules
diacerein
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63472313
2012
France
summary of product characteristics
package leaflet
diacerein
capsules
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_rambaxy_21-09-2011_avis_11154.pdf
http://www.has-sante.fr/portail/jcms/c_1106789/diacereine-ranbaxy
2011
France
French
evaluation of the transparency committee
anthraquinones
diacerein
administration, oral
anti-inflammatory agents
treatment outcome
insurance, health, reimbursement
drugs, generic
diacerein
osteoarthritis, knee
osteoarthritis, hip
---
http://www.has-sante.fr/portail/jcms/c_1106788/diacereine-arrow
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_arrow_21-09-2011_avis_11144.pdf
2011
France
French
evaluation of the transparency committee
anthraquinones
administration, oral
drugs, generic
diacerein
diacerein
treatment outcome
anti-inflammatory agents
osteoarthritis, knee
osteoarthritis, hip
insurance, health, reimbursement
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_qualimed_21-09-2011_avis_11153.pdf
http://www.has-sante.fr/portail/jcms/c_1106806/diacereine-qualimed
2011
France
French
evaluation of the transparency committee
anthraquinones
diacerein
administration, oral
drugs, generic
insurance, health, reimbursement
treatment outcome
anti-inflammatory agents
diacerein
osteoarthritis, hip
osteoarthritis, knee
---
http://www.has-sante.fr/portail/jcms/c_1106807/diacereine-sandoz
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_sandoz_21-09-2011_avis_11156.pdf
2011
France
French
evaluation of the transparency committee
anthraquinones
diacerein
administration, oral
anti-inflammatory agents
drugs, generic
treatment outcome
insurance, health, reimbursement
diacerein
osteoarthritis, hip
osteoarthritis, knee
---
http://www.has-sante.fr/portail/jcms/c_1106809/diacereine-eg
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_eg_21-09-2011_avis_11147.pdf
2011
France
French
evaluation of the transparency committee
anthraquinones
diacerein
anti-inflammatory agents
administration, oral
drugs, generic
treatment outcome
insurance, health, reimbursement
diacerein
osteoarthritis, knee
osteoarthritis, hip
---
http://www.has-sante.fr/portail/jcms/c_1106810/art-50
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/art_50__21-09-2011_avis_11088.pdf
2011
France
French
evaluation of the transparency committee
anthraquinones
diacerein
administration, oral
insurance, health, reimbursement
treatment outcome
anti-inflammatory agents
diacerein
osteoarthritis, knee
osteoarthritis, hip
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_mylan_21-09-2011_avis_11149.pdf
http://www.has-sante.fr/portail/jcms/c_1106812/diacereine-mylan
2011
France
French
evaluation of the transparency committee
anthraquinones
diacerein
anti-inflammatory agents
administration, oral
drugs, generic
treatment outcome
insurance, health, reimbursement
diacerein
osteoarthritis, knee
osteoarthritis, hip
---
http://www.has-sante.fr/portail/jcms/c_1106816/diacereine-ratiopharm
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_ratiopharm_21-09-2011_avis_11155.pdf
2011
France
French
evaluation of the transparency committee
anthraquinones
diacerein
administration, oral
drugs, generic
anti-inflammatory agents
treatment outcome
insurance, health, reimbursement
diacerein
osteoarthritis, hip
osteoarthritis, knee
---
http://www.has-sante.fr/portail/jcms/c_1106835/diacereine-teva
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_teva_21-09-2011_avis_11157.pdf
2011
France
French
evaluation of the transparency committee
diacerein
administration, oral
treatment outcome
insurance, health, reimbursement
anti-inflammatory agents
drugs, generic
diacerein
osteoarthritis, hip
osteoarthritis, knee
anthraquinones
---
http://www.has-sante.fr/portail/jcms/c_1106862/diacereine-winthrop
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_winthrop_21-09-2011_avis_11158.pdf
2011
France
French
evaluation of the transparency committee
diacerein
administration, oral
treatment outcome
insurance, health, reimbursement
drugs, generic
anti-inflammatory agents
osteoarthritis, hip
osteoarthritis, knee
diacerein
anthraquinones
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_actavis_21-09-2011_avis_11143.pdf
http://www.has-sante.fr/portail/jcms/c_1106843/diacereine-actavis
2011
France
French
evaluation of the transparency committee
diacerein
administration, oral
drugs, generic
insurance, health, reimbursement
treatment outcome
anti-inflammatory agents
osteoarthritis, hip
osteoarthritis, knee
diacerein
anthraquinones
---
http://www.has-sante.fr/portail/jcms/c_1106851/diacereine-cristers
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_cristers_21-09-2011_avis_11146.pdf
2011
France
French
evaluation of the transparency committee
diacerein
administration, oral
drugs, generic
insurance, health, reimbursement
treatment outcome
anti-inflammatory agents
osteoarthritis, knee
osteoarthritis, hip
diacerein
anthraquinones
---
http://www.has-sante.fr/portail/jcms/c_1106861/diacereine-biogaran
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_biogaran_21-09-2011_avis_11145.pdf
2011
France
French
evaluation of the transparency committee
diacerein
administration, oral
drugs, generic
insurance, health, reimbursement
treatment outcome
anti-inflammatory agents
osteoarthritis, hip
osteoarthritis, knee
diacerein
anthraquinones
---
http://www.has-sante.fr/portail/jcms/c_1106842/diacereine-evolugen
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_evolugen_21-09-2011_avis_11148.pdf
2011
France
French
evaluation of the transparency committee
diacerein
administration, oral
drugs, generic
treatment outcome
insurance, health, reimbursement
anti-inflammatory agents
osteoarthritis, hip
osteoarthritis, knee
diacerein
anthraquinones
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_negma_21-09-2011_avis_11151.pdf
http://www.has-sante.fr/portail/jcms/c_1106866/diacereine-negma
2011
France
French
evaluation of the transparency committee
diacerein
administration, oral
drugs, generic
treatment outcome
insurance, health, reimbursement
anti-inflammatory agents
osteoarthritis, hip
osteoarthritis, knee
diacerein
anthraquinones
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/diacerine_pharma2000_21-09-2011_avis_11152.pdf
http://www.has-sante.fr/portail/jcms/c_1106818/diacereine-pharma-2000
2011
France
French
evaluation of the transparency committee
diacerein
administration, oral
diacerein
anti-inflammatory agents
osteoarthritis, knee
osteoarthritis, hip
treatment outcome
drugs, generic
insurance, health, reimbursement
anthraquinones
---
http://www.has-sante.fr/portail/jcms/c_1106805/zondar
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/zondar_21-09-2011_avis_11259.pdf
2011
France
French
evaluation of the transparency committee
anthraquinones
diacerein
administration, oral
anti-inflammatory agents
treatment outcome
insurance, health, reimbursement
diacerein
osteoarthritis, hip
osteoarthritis, knee
---