tissue-factor-pathway inhibitor 2

Preferred Label : tissue-factor-pathway inhibitor 2;

MeSH note : glycoprotein containing 20% carbohydrate which moves as a beta(1) globulin on electrophoresis; MW 36,000; TFPI-2 is an important regulator of the extrinsic pathway of blood coagulation; a factor VIIA antagonist; present in placenta, maternal serum in late pregnancy, liver, heart, pancreas, and other tissues; a serine protease inhibitor; GenBank L27624 (human); REfSeq NM_006528 (human), NM_009364 (mouse);

CISMeF synonym : TFPI2 protein, human; Tfpi2 protein, mouse;

MeSH synonym : placental protein 5; placenta-specific protein 5; TFPI-2; MSPI protein; tissue factory pathway inhibitor-2; PP5; matrix-associated serine protease inhibitor;

MeSH hyponym : PP5 protein, human; Placental protein 5, human; tissue factor pathway inhibitor 2 protein, human; PP5 protein, mouse; tissue factor pathway inhibitor 2 protein, mouse;

Is substance : O;

Details

Origin ID

C021240;

UMLS CUI

C0071196;

MeSH indexing information
- factor VIIa [MeSH Descriptor]
- lipoproteins [MeSH Descriptor]
MeSH term(s) associated for indexing
- glycoproteins [MeSH Descriptor]
Pharmacological action(s)
- serine proteinase inhibitors [MeSH Descriptor]
Record concept(s)
- TFPI2 protein, human [MeSH concept]
- Tfpi2 protein, mouse [MeSH concept]
- Tfpi2 protein, rat [MeSH concept]
- tissue-factor-pathway inhibitor 2 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Placental protein 5 (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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