Myotonin-Protein Kinase

Preferred Label : Myotonin-Protein Kinase;

MeSH definition : Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1.;

MeSH synonym : Kinase, Myotonin-Protein; Myotonin Protein Kinase; DM-Kinase; DM Kinase; Myotonic Dystrophy Protein Kinase; DMPK Protein; Protein, DMPK; MDGP Protein; Protein, MDGP; MDPK Protein; Protein, MDPK; DM Protein Kinase; Kinase, DM Protein; Protein Kinase, DM; DM1PK Protein; Protein, DM1PK;

Registry Number MeSH : EC 2.7.11.1;

Wikipedia link : https://en.wikipedia.org/wiki/Myotonic dystrophy protein kinase;

UNII : EC 2.7.11.1;

Details

Origin ID

D065636;

UMLS CUI

C0216045;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Myotonin-Protein Kinase [MeSH concept]
Related MeSH Supplementary Concept(s)
- CDC42BPA protein, human [MeSH Supplementary Concept]
- CDC42BPB protein, human [MeSH Supplementary Concept]
- DMPK protein, human [MeSH Supplementary Concept]
- DMPK protein, mouse [MeSH Supplementary Concept]
- Dmpk protein, rat [MeSH Supplementary Concept]
See also
- myotonic dystrophy [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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