Preferred Label : solute carrier family 12, member 1;
MeSH definition : Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption
of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE.
Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME.;
MeSH synonym : Bumetanide-Sensitive Sodium-(Potassium)-Chloride cotransporter 2; Kidney-Specific Na-K-Cl symporter; kidney specific na K cl symporter; Na-K-Cl symporter, Kidney-Specific; symporter, Kidney-Specific Na-K-Cl; NKCC2 protein; protein, NKCC2; SLC12A1 cotransporter; cotransporter, SLC12A1; SLC12A1 protein; protein, SLC12A1; BSC1 transport protein; protein, BSC1 transport; transport protein, BSC1; NKCC2 cotransporter; cotransporter, NKCC2;
Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption
of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE.
Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME.
Allowable qualifiers