filamins - CISMeF

Preferred Label : filamins;

MeSH definition : A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences.;

MeSH synonym : filamin;

CISMeF synonym : 1, filamin; A, filamin; B, filamin; C, filamin;

MeSH hyponym : merofilamins; filamin A; filamin C; filamin B; beta-Filamin; beta Filamin; beta-Filamins; Filamin 1-Like Protein; 1-Like Protein, Filamin; 1-Like Proteins, Filamin; Filamin 1 Like Protein; Filamin 1-Like Proteins; Protein, Filamin 1-Like; Proteins, Filamin 1-Like; Merofilamin; Filamin 1; alpha-Filamin; alpha Filamin; alpha-Filamins; 280 kDa Actin-Binding Protein; 280 kDa Actin Binding Protein; Cs, Filamin; Filamin Cs;

Wikipedia link : https://en.wikipedia.org/wiki/Filamin;

Is substance : O;

Details

Origin ID

D064448;

UMLS CUI

C0060383;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Filamin [FMA entity]
- Filamin C [OMIM gene]
- Filamin a [OMIM gene]
- Filamin b [OMIM gene]
- Filamin-A [NCIt concept]
- Filamin-C [NCIt concept]
- filamin A [ORDO Gene]
- filamin A [HGNC gene]
- filamin B [ORDO Gene]
- filamin B [HGNC gene]
- filamin C [ORDO Gene]
- filamin C [HGNC gene]
Record concept(s)
- filamin A [MeSH concept]
- filamin B [MeSH concept]
- filamin C [MeSH concept]
- filamins [MeSH concept]
- merofilamins [MeSH concept]
Related MeSH Supplementary Concept(s)
- FLN-1 protein, C elegans [MeSH Supplementary Concept]
- FLNA protein, human [MeSH Supplementary Concept]
- FLNB protein, human [MeSH Supplementary Concept]
- FLNB protein, mouse [MeSH Supplementary Concept]
- FLNC protein, human [MeSH Supplementary Concept]
- FlnA protein, mouse [MeSH Supplementary Concept]
- cher protein, drosophila [MeSH Supplementary Concept]
- filamin protein, chicken [MeSH Supplementary Concept]
- fln protein, drosophila [MeSH Supplementary Concept]
- flncb protein, zebrafish [MeSH Supplementary Concept]
- jbug protein, Drosophila [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Filamin [FMA entity]

Keyword's position in hierarchy(ies) :

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