MeSH definition : Geminin inhibits DNA replication by preventing the incorporation of MCM complex into
pre-replication complex. It is absent during G1 phase of the CELL CYCLE and accumulates
through S, G2,and M phases. It is degraded at the metaphase-anaphase transition by
the ANAPHASE-PROMOTING COMPLEX-CYCLOSOME.;
Geminin inhibits DNA replication by preventing the incorporation of MCM complex into
pre-replication complex. It is absent during G1 phase of the CELL CYCLE and accumulates
through S, G2,and M phases. It is degraded at the metaphase-anaphase transition by
the ANAPHASE-PROMOTING COMPLEX-CYCLOSOME.