Mad2 proteins - CISMeF

Preferred Label : Mad2 proteins;

MeSH definition : Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.;

MeSH synonym : Mad2 mitotic arrest deficient-like 1 proteins;

Is substance : O;

Details

Origin ID

D064246;

UMLS CUI

C3658249;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Mad2 proteins [MeSH concept]
Related MeSH Supplementary Concept(s)
- MAD2 (Mitotic arrest deficient protein 2), arabidopsis [MeSH Supplementary Concept]
- MAD2 protein, S cerevisiae [MeSH Supplementary Concept]
- MAD2L1 protein, human [MeSH Supplementary Concept]
- MAD2L2 protein, human [MeSH Supplementary Concept]
- MAD2L2 protein, xenopus [MeSH Supplementary Concept]
- Mad2 protein, drosophila [MeSH Supplementary Concept]
- Mad2l1 protein, mouse [MeSH Supplementary Concept]
- Mad2l2 protein, mouse [MeSH Supplementary Concept]
- Mad2l2 protein, rat [MeSH Supplementary Concept]
- mad2 protein, S pombe [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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