MeSH definition : Highly conserved proteins that specifically bind to and activate the anaphase-promoting
complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory
proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of
anaphase, and cyclin proteolysis during mitosis.;
Highly conserved proteins that specifically bind to and activate the anaphase-promoting
complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory
proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of
anaphase, and cyclin proteolysis during mitosis.