MeSH definition : Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting
complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core,
and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex.;
Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting
complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core,
and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex.