Preferred Label : Apc8 subunit, Anaphase-Promoting Complex-Cyclosome;
MeSH definition : A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple
34-amino-acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6,
and Apc7, have been shown to mediate protein-protein interactions, suggesting that
Apc8 may assist in coordinating the juxtaposition of the catalytic and substrate recognition
module subunits relative to coactivators and APC-C inhibitors.;
MeSH synonym : Apc8 subunit, anaphase promoting complex cyclosome; Apc8 subunit, Anaphase-Promoting complex; Apc8 subunit, anaphase promoting complex; Anapc8;
Is substance : O;
Origin ID : D064196;
UMLS CUI : C3537339;
Allowable qualifiers
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple
34-amino-acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6,
and Apc7, have been shown to mediate protein-protein interactions, suggesting that
Apc8 may assist in coordinating the juxtaposition of the catalytic and substrate recognition
module subunits relative to coactivators and APC-C inhibitors.
