Apc2 subunit, Anaphase-Promoting Complex-Cyclosome

Preferred Label : Apc2 subunit, Anaphase-Promoting Complex-Cyclosome;

MeSH definition : Together with the Apc11 subunit, forms the catalytic core of the E3 ubiquitin ligase anaphase-promoting complex (APC-C). Its N-terminus has cullin domains which associate with the RING FINGER DOMAINS of Apc11. Apc2 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions.;

MeSH synonym : Apc2 subunit, anaphase promoting complex cyclosome; Apc2 subunit, Anaphase-Promoting complex; Apc2 subunit, anaphase promoting complex; Anapc2;

Registry Number MeSH : EC 6.3.2.19; EC 2.3.2.27;

Is substance : O;

UNII : EC 2.3.2.27;

Details

Origin ID

D064190;

UMLS CUI

C3543438;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Anaphase-promoting complex, subunit 2 [OMIM gene]
Record concept(s)
- Apc2 subunit, Anaphase-Promoting Complex-Cyclosome [MeSH concept]
Related MeSH Supplementary Concept(s)
- ANAPC2 protein, human [MeSH Supplementary Concept]
- APC-2 protein, C elegans [MeSH Supplementary Concept]
- APC2 protein, S cerevisiae [MeSH Supplementary Concept]
- Anapc2 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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