aurora kinase A

Preferred Label : aurora kinase A;

MeSH definition : An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE. Aurora A overexpression in many malignant tumor types suggests that it may be directly involved in NEOPLASTIC CELL TRANSFORMATION.;

MeSH synonym : aurora A kinase; aurora A kinases; aurora kinases A; STK15 kinase; AURORA2 protein; AuroraA kinase; Breast-Tumor-Amplified kinase; breast tumor amplified kinase; BTAK protein; Serine-Threonine protein kinase 15; serine threonine protein kinase 15; AURKA; Aurora-A kinase;

Registry Number MeSH : EC 2.7.11.1;

Wikipedia link : https://en.wikipedia.org/wiki/Aurora a kinase;

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D064096;

UMLS CUI

C0971285;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- aurora kinase A [MeSH concept]
Related MeSH Supplementary Concept(s)
- AURKA protein, human [MeSH Supplementary Concept]
- air-1 protein, C elegans [MeSH Supplementary Concept]
- aurA protein, Drosophila [MeSH Supplementary Concept]
- aurka protein, mouse [MeSH Supplementary Concept]
- aurka protein, rat [MeSH Supplementary Concept]
See also inter- (CISMeF)
- AURKA Gene [NCIt concept]
- Aurora kinase a [OMIM gene]
- aurora kinase A [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Aurora Kinase A [NCIt concept]

Keyword's position in hierarchy(ies) :

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