NAV1.6 Voltage-Gated sodium channel

Preferred Label : NAV1.6 Voltage-Gated sodium channel;

MeSH definition : A voltage-gated sodium channel subtype found widely expressed in neurons of the central and peripheral nervous systems. Defects in the SCN8A gene which codes for the alpha subunit of this sodium channel are associated with ATAXIA and cognitive deficits.;

MeSH synonym : NAV1.6 voltage gated sodium channel; type 8 Voltage-Gated sodium channel; type 8 voltage gated sodium channel; Voltage-Gated sodium channel type 8; voltage gated sodium channel type 8;

MeSH hyponym : Voltage-Gated sodium channel type 8 subunit alpha; Voltage Gated Sodium Channel Type 8 Subunit alpha; SCN8A Sodium Channel alpha Subunit;

Is substance : O;

Details

Origin ID

D062557;

UMLS CUI

C3494337;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- NAV1.6 Voltage-Gated sodium channel [MeSH concept]
- Voltage-Gated sodium channel type 8 subunit alpha [MeSH concept]
Related MeSH Supplementary Concept(s)
- SCN8A protein, human [MeSH Supplementary Concept]
- Scn8a protein, mouse [MeSH Supplementary Concept]
- Scn8a protein, rat [MeSH Supplementary Concept]
- scn8aa protein, zebrafish [MeSH Supplementary Concept]
Related MeSH term(s)
- Voltage-Gated sodium channel agonists [MeSH Descriptor]
- Voltage-Gated sodium channel blockers [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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