NAV1.2 Voltage-Gated sodium channel

Preferred Label : NAV1.2 Voltage-Gated sodium channel;

MeSH definition : A voltage-gated sodium channel subtype that mediates the sodium ion permeability of excitable membranes. Defects in the SCN2A gene which codes for the alpha subunit of this sodium channel are associated with benign familial infantile seizures type 3, and early infantile epileptic encephalopathy type 11.;

MeSH synonym : NAV1.2 voltage gated sodium channel; type 2 Voltage-Gated sodium channel; type 2 voltage gated sodium channel; Voltage-Gated sodium channel type 2; voltage gated sodium channel type 2;

MeSH hyponym : Voltage-Gated sodium channel type 2 subunit alpha; Voltage Gated Sodium Channel Type 2 Subunit alpha; Voltage-Gated Sodium Channel Type 2 alpha Subunit; Voltage Gated Sodium Channel Type 2 alpha Subunit; Sodium Channel, Voltage-Gated, Type II, alpha 1 Subunit; Sodium Channel Protein Type 2 Subunit alpha; Sodium Channel, Voltage-Gated, Type II, alpha 1; NAV1.2 alpha Subunit; SCN2A Sodium Channel alpha Subunit;

Is substance : O;

Details

Origin ID

D062551;

UMLS CUI

C3494330;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Sodium Channel Protein Type 2 Subunit Alpha [NCIt concept]
Record concept(s)
- NAV1.2 Voltage-Gated sodium channel [MeSH concept]
- Voltage-Gated sodium channel type 2 subunit alpha [MeSH concept]
Related MeSH Supplementary Concept(s)
- SCN2A protein, human [MeSH Supplementary Concept]
- Scn2A protein, rat [MeSH Supplementary Concept]
- Scn2a protein, mouse [MeSH Supplementary Concept]
Related MeSH term(s)
- Voltage-Gated sodium channel agonists [MeSH Descriptor]
- Voltage-Gated sodium channel blockers [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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