NAV1.1 Voltage-Gated sodium channel

Preferred Label : NAV1.1 Voltage-Gated sodium channel;

MeSH definition : A voltage-gated sodium channel subtype that is predominantly expressed in the CENTRAL NERVOUS SYSTEM. Defects in the SCN1A gene which codes for the alpha subunit of this sodium channel are associated with DRAVET SYNDROME, generalized epilepsy with febrile seizures plus, type 2 (GEFS 2), and familial hemiplegic migraine type 3.;

MeSH synonym : NAV1.1 voltage gated sodium channel; Voltage-Gated sodium channel type 1; voltage gated sodium channel type 1; type 1 Voltage-Gated sodium channel; type 1 voltage gated sodium channel;

MeSH hyponym : Voltage-Gated sodium channel type 1 subunit alpha; Voltage Gated Sodium Channel Type 1 Subunit alpha; Sodium Channel, Voltage-Gated, Type I, alpha Protein; SCN1A Sodium Channel alpha Subunit; Voltage-Gated Sodium Channel Type 1 alpha Subunit; Voltage Gated Sodium Channel Type 1 alpha Subunit; NAV1.1 alpha Subunit; alpha Subunit, NAV1.1;

Is substance : O;

Détails

Origin ID

D062550;

UMLS CUI

C3494329;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- SCN1A wt Allele [NCIt concept]
Record concept(s)
- NAV1.1 Voltage-Gated sodium channel [MeSH concept]
- Voltage-Gated sodium channel type 1 subunit alpha [MeSH concept]
Related MeSH Supplementary Concept(s)
- SCN1A protein, human [MeSH Supplementary Concept]
- Scn1a protein, mouse [MeSH Supplementary Concept]
- Scn1a protein, rat [MeSH Supplementary Concept]
- scn1laa protein, zebrafish [MeSH Supplementary Concept]
Related MeSH term(s)
- Voltage-Gated sodium channel agonists [MeSH Descriptor]
- Voltage-Gated sodium channel blockers [MeSH Descriptor]
See also
- epilepsies, myoclonic [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Position du mot-clé dans l'(les) arborescence(s) :

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