MeSH definition : An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays
a role in controlling the paracellular permeability of polarized cells. Mutations
in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis
(NISCH) Syndrome.;
An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays
a role in controlling the paracellular permeability of polarized cells. Mutations
in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis
(NISCH) Syndrome.