CTLA-4 antigen

Preferred Label : CTLA-4 antigen;

MeSH definition : An inhibitory T CELL receptor that is closely related to CD28 ANTIGEN. It has specificity for CD80 ANTIGEN and CD86 ANTIGEN and acts as a negative regulator of peripheral T cell function. CTLA-4 antigen is believed to play role in inducing PERIPHERAL TOLERANCE.;

MeSH synonym : antigen, CTLA-4; cytotoxic T-Lymphocyte-Associated antigen 4; cytotoxic T lymphocyte associated antigen 4; cytotoxic T-Lymphocyte antigen 4; cytotoxic T lymphocyte antigen 4; antigens, CD152; CD152 antigens; CD152 antigen; antigen, CD152; CTLA 4 antigen; CTLA-4 Protein; CTLA 4 Protein;

Is substance : O;

Details

Origin ID

D060908;

UMLS CUI

C0111208;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Record concept(s)
- CTLA-4 antigen [MeSH concept]
Related MeSH Supplementary Concept(s)
- ASP2408 [MeSH Supplementary Concept]
- CTLA4 protein, human [MeSH Supplementary Concept]
- Ctla4 protein, mouse [MeSH Supplementary Concept]
- Ctla4 protein, rat [MeSH Supplementary Concept]
See also
- Abatacept [MeSH Descriptor]
- Ipilimumab [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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