endoplasmic Reticulum-Associated degradation

Preferred Label : endoplasmic Reticulum-Associated degradation;

MeSH definition : A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.;

MeSH synonym : degradation, endoplasmic Reticulum-Associated; Reticulum-Associated degradation, endoplasmic; ERAD pathway; ERAD pathways; pathway, ERAD; pathways, ERAD; endoplasmic reticulum associated degradation;

Details

Origin ID

D060746;

UMLS CUI

C3178997;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ERAD pathway [GO term]
Record concept(s)
- endoplasmic Reticulum-Associated degradation [MeSH concept]
See also
- endoplasmic reticulum stress [MeSH Descriptor]
- proteolysis [MeSH Descriptor]
- ubiquitination [MeSH Descriptor]
- unfolded protein response [MeSH Descriptor]
Semantic type(s)
- Molecular Function [UMLS semantic type]
UMLS correspondences (same concept)
- ERAD pathway [GO term]

Keyword's position in hierarchy(ies) :

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