Cyclin-Dependent kinase 8

Preferred Label : Cyclin-Dependent kinase 8;

MeSH definition : A CYCLIN C dependent kinase that is an important component of the mediator complex. The enzyme is activated by its interaction with CYCLIN C and plays a role in transcriptional regulation by phosphorylating RNA POLYMERASE II.;

MeSH synonym : Cdk8 protein kinase; cell division protein kinase 8; Cyclin-Dependent kinase, Cdk8; Cdk8 Cyclin-Dependent kinase; Cdk8 cyclin dependent kinase; kinase, Cdk8 Cyclin-Dependent; kinase, Cdk8 protein; protein kinase, Cdk8; cyclin dependent kinase 8;

MeSH Related Number : EC 2.7.11.23;

Registry Number MeSH : EC 2.7.11.22;

Is substance : O;

UNII : EC 2.7.11.22;

Details

Origin ID

D056850;

UMLS CUI

C2720173;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Cyclin-Dependent Kinase 8 [NCIt concept]
Record concept(s)
- Cyclin-Dependent kinase 8 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CDK8 protein, arabidopsis [MeSH Supplementary Concept]
- CDK8 protein, human [MeSH Supplementary Concept]
- Cdk8 protein, drosophila [MeSH Supplementary Concept]
- Cdk8 protein, mouse [MeSH Supplementary Concept]
- SSN3 protein, S cerevisiae [MeSH Supplementary Concept]
- cdk8 protein, zebrafish [MeSH Supplementary Concept]
- srb10 protein, S pombe [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients