MeSH definition : A family of histone demethylases that share a conserved Jumonji C domain. The enzymes
function via an iron-dependent dioxygenase mechanism that couples the conversion of
2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.;
A family of histone demethylases that share a conserved Jumonji C domain. The enzymes
function via an iron-dependent dioxygenase mechanism that couples the conversion of
2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.