MeSH definition : A large family of structurally-related transcription factors that were originally
discovered based upon their close sequence homology to an HMG-box domain found in
SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles
in regulating CELL DIFFERENTIATION. The numerous members of this family are organized
in several subgroups according to structural identities found within the proteins.;
MeSH synonym : SRY (Sex determining region Y)-Box proteins; transcription factors, SOX; SOX family of transcription factors; SOX transcription factor family;
MeSH annotation : do not confuse entry term SRY (SEX DETERMINING REGION Y)-BOX PROTEINS with SRY SEX-DETERMINING
REGION PROTEIN see SEX-DETERMINING REGION Y PROTEIN;
A large family of structurally-related transcription factors that were originally
discovered based upon their close sequence homology to an HMG-box domain found in
SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles
in regulating CELL DIFFERENTIATION. The numerous members of this family are organized
in several subgroups according to structural identities found within the proteins.