acid ceramidase

Preferred Label : acid ceramidase;

MeSH definition : A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.;

Registry Number MeSH : EC 3.5.1.23;

Is substance : O;

UNII : EC 3.5.1.23;

Details

Origin ID

D055573;

UMLS CUI

C2350443;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Acid Ceramidase [NCIt concept]
Indexing information
- LCL-464 [MeSH Supplementary Concept]
- N-(1-(4-nitrophenyl)-1,3-dihydroxyprop-2-yl)tetradecanamide [MeSH Supplementary Concept]
Record concept(s)
- acid ceramidase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ASAH1 protein, human [MeSH Supplementary Concept]
- Asah1 protein, mouse [MeSH Supplementary Concept]
- Asah1 protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- farber lipogranulomatosis [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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