bone morphogenetic protein 5

Preferred Label : bone morphogenetic protein 5;

MeSH definition : A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator of the growth of CHONDROCYTES and the synthesis of cartilage matrix proteins. Evidence for its role in cartilage formation can be seen in MICE, where genetic mutations that cause loss of bone morphogenetic protein 5 function result in the formation of small malformed ears.;

MeSH synonym : BMP-5;

Wikipedia link : https://en.wikipedia.org/wiki/Bone morphogenetic protein 5;

Is substance : O;

Details

Origin ID

D055417;

UMLS CUI

C0537464;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- BMP5 Gene [NCIt concept]
- Bone morphogenetic protein 5 [OMIM gene]
- bone morphogenetic protein 5 [HGNC gene]
Currated CISMeF NLP mapping
- Bone Morphogenetic Protein 5 [NCIt concept]
Record concept(s)
- bone morphogenetic protein 5 [MeSH concept]
Related MeSH Supplementary Concept(s)
- BMP5 protein, human [MeSH Supplementary Concept]
- BMP5 protein, rat [MeSH Supplementary Concept]
- Bmp5 protein, mouse [MeSH Supplementary Concept]
- Bmp5 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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