fatty acid synthase, type I

Preferred Label : fatty acid synthase, type I;

MeSH definition : Animal form of fatty acid synthase which is encoded by a single gene and consists of seven catalytic domains and is functional as a homodimer. It is overexpressed in some NEOPLASMS and is a target in humans of some ANTINEOPLASTIC AGENTS and some ANTI-OBESITY AGENTS.;

CISMeF synonym : fatty acid synthetase complex, type I; EC 6.- (Fatty acid synthase, mammalian);

MeSH hyponym : fatty acid synthase, animal form; fatty acid synthase, mammalian;

MeSH Related Number : EC 1.1.1.100; EC 2.3.1.38; EC 2.3.1.39; EC 2.3.1.41; EC 3.1.2.14; EC 4.2.1.59;

Registry Number MeSH : EC 6.-; EC 2.3.1.85;

Is substance : O;

UNII : EC 2.3.1.85;

Details

Origin ID

D054890;

UMLS CUI

C3658369;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Fatty Acid Synthase [NCIt concept]
Record concept(s)
- fatty acid synthase, animal form [MeSH concept]
- fatty acid synthase, mammalian [MeSH concept]
- fatty acid synthase, type I [MeSH concept]
Related MeSH Supplementary Concept(s)
- FASN protein, human [MeSH Supplementary Concept]
- FASN protein, rat [MeSH Supplementary Concept]
- Fasn protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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