ring finger domains

Preferred Label : ring finger domains;

MeSH definition : A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2-Cysteine, where X is any amino acid. The RING finger motif binds two atoms of zinc, with each zinc atom ligated tetrahedrally by either four cysteines or three cysteines and a histidine. The motif also forms into a unitary structure with a central cross-brace region and is found in many proteins that are involved in protein-protein interactions. The acronym RING stands for Really Interesting New Gene.;

MeSH synonym : ring finger domain; domains, ring finger; ring finger motifs; ring finger motif;

Details

Origin ID

D054829;

UMLS CUI

C1521759;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Currated CISMeF NLP mapping
- Ring Finger Domain [NCIt concept]
Indexing information
- CULL-RING ligase, human [MeSH Supplementary Concept]
- DAL2 protein, arabidopsis [MeSH Supplementary Concept]
- Gid9 protein, saccharomyces cerevisiae [MeSH Supplementary Concept]
- LTN1 protein, human [MeSH Supplementary Concept]
- MSL2 protein, human [MeSH Supplementary Concept]
- PLR-1 protein, C elegans [MeSH Supplementary Concept]
- Pja2 protein, rat [MeSH Supplementary Concept]
- RC3H2 protein, human [MeSH Supplementary Concept]
- RGLG2 protein, arabidopsis [MeSH Supplementary Concept]
- RING1a protein, arabidopsis [MeSH Supplementary Concept]
- RING1b protein, arabidopsis [MeSH Supplementary Concept]
- RMND5A protein, human [MeSH Supplementary Concept]
- RNF-121 protein, C elegans [MeSH Supplementary Concept]
- RNF10 protein, rat [MeSH Supplementary Concept]
- RNF123 protein, human [MeSH Supplementary Concept]
- RNF125 protein, mouse [MeSH Supplementary Concept]
- RNF126 protein, human [MeSH Supplementary Concept]
- RNF138 protein, human [MeSH Supplementary Concept]
- RNF144A protein, human [MeSH Supplementary Concept]
- RNF149 protein, human [MeSH Supplementary Concept]
- RNF152 protein, human [MeSH Supplementary Concept]
- RNF165 protein, mouse [MeSH Supplementary Concept]
- RNF166 protein, human [MeSH Supplementary Concept]
- RNF185 protein, human [MeSH Supplementary Concept]
- RNF186 protein, human [MeSH Supplementary Concept]
- RNF213 protein, human [MeSH Supplementary Concept]
- RNF217 protein, human [MeSH Supplementary Concept]
- Rchy1 protein, rat [MeSH Supplementary Concept]
- Rnf103 protein, mouse [MeSH Supplementary Concept]
- Rnf146 protein, mouse [MeSH Supplementary Concept]
- Rnf213 protein, rat [MeSH Supplementary Concept]
- SAG protein, mouse [MeSH Supplementary Concept]
- SH3RF2 protein, human [MeSH Supplementary Concept]
- SH3RF3 protein, human [MeSH Supplementary Concept]
- SP1 protein, Arabidopsis [MeSH Supplementary Concept]
- TRIM50 protein, human [MeSH Supplementary Concept]
- TRIM69 protein, human [MeSH Supplementary Concept]
- Uhrf1 protein, xenopus [MeSH Supplementary Concept]
- WAV3 protein, arabidopsis [MeSH Supplementary Concept]
- elfless protein, drosophila [MeSH Supplementary Concept]
- lnx2b protein, zebrafish [MeSH Supplementary Concept]
- pdzrn3b protein, zebrafish [MeSH Supplementary Concept]
- qin protein, drosophila [MeSH Supplementary Concept]
- roquin-2 protein, mouse [MeSH Supplementary Concept]
Record concept(s)
- RING finger domains [MeSH concept]
See also
- Peroxisomal Biogenesis Factor 2 [MeSH Descriptor]
- Tripartite Motif-Containing Protein 28 [MeSH Descriptor]
- proto-oncogene proteins c-cbl [MeSH Descriptor]
Semantic type(s)
- Cell Component [UMLS semantic type]
UMLS correspondences (same concept)
- Ring Finger Domain [NCIt concept]

Keyword's position in hierarchy(ies) :

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