G-Protein-Coupled receptor kinase 2

Preferred Label : G-Protein-Coupled receptor kinase 2;

MeSH definition : A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS. It may play an essential role in regulating myocardial contractile response.;

MeSH synonym : beta-adrenergic receptor kinase 1; beta adrenergic receptor kinase 1; G protein coupled receptor kinase 2;

MeSH Related Number : EC 2.7.11.16;

Registry Number MeSH : EC 2.7.11.15; EC 2.7.11.16;

Is substance : O;

UNII : EC 2.7.11.16;

Details

Origin ID

D054769;

UMLS CUI

C0753114;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Beta-Adrenergic Receptor Kinase 1 [NCIt concept]
Record concept(s)
- G-Protein-Coupled receptor kinase 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- GRK2 protein, human [MeSH Supplementary Concept]
- GRK2 protein, mouse [MeSH Supplementary Concept]
- Gprk2 protein, drosophila [MeSH Supplementary Concept]
- Grk2 protein, rat [MeSH Supplementary Concept]
- muscarinic receptor kinase [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Beta-Adrenergic Receptor Kinase 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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