MeSH definition : A structurally-diverse family of intracellular-signaling adaptor proteins that selectively
tether specific protein kinase A subtypes to distinct subcellular sites. They play
a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over
fifty members of this family exist, most of which bind specifically to regulatory
subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE
RIIALPHA or CAMP PROTEIN KINASE RIIBETA.;
MeSH synonym : protein kinase a anchor proteins; anchor proteins, a-kinase; A-Kinase anchor proteins; A-Kinase Anchoring Proteins; A Kinase Anchoring Proteins; A-Kinase Anchoring Protein; A Kinase Anchoring Protein; Anchoring Protein, A-Kinase; Protein, A-Kinase Anchoring;
A structurally-diverse family of intracellular-signaling adaptor proteins that selectively
tether specific protein kinase A subtypes to distinct subcellular sites. They play
a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over
fifty members of this family exist, most of which bind specifically to regulatory
subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE
RIIALPHA or CAMP PROTEIN KINASE RIIBETA.