Preferred Label : cyclic nucleotide phosphodiesterases, type 6;
MeSH definition : A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC
GMP. It is found predominantly in the outer segment PHOTORECEPTOR CELLS of the RETINA.
It is comprised of two catalytic subunits, referred to as alpha and beta, that form
a dimer. In addition two regulatory subunits, referred to as gamma and delta, modulate
the activity and localization of the enzyme.;
MeSH synonym : pde6 phosphodiesterases; phosphodiesterase type 6; phosphodiesterase 6; phosphodiesterase 6, retinal; phosphodiesterases, pde6; retinal phosphodiesterase 6;
MeSH hyponym : cyclic nucleotide phosphodiesterases, type 6, beta subunit; cyclic nucleotide phosphodiesterases, type 6, delta subunit; cyclic nucleotide phosphodiesterases, type 6, alpha subunit; cyclic nucleotide phosphodiesterases, type 6, gamma subunit; beta Subunit, PDE6; PDE6 beta Subunit; Retinal Phosphodiesterase, beta Subunit; PDE6, beta Subunit; beta Subunit PDE6; Rod cGMP Phosphodiesterase, beta Subunit; cGMP-PDE gamma Subunit; cGMP PDE gamma Subunit; gamma Subunit, cGMP-PDE; gamma Subunit, cGMP Phosphodiesterase; PDE6, alpha Subunit; alpha Subunit PDE6; Retinal Phosphodiesterase, alpha Subunit; alpha Subunit, PDE6; PDE6 alpha Subunit; delta Subunit, PDE6; PDE6 delta Subunit; cGMP Phosphodiesterase delta Subunit; PDE6, delta Subunit; delta Subunit PDE6; Retinal Phosphodiesterase, delta Subunit;
CISMeF hyponym : EC 3.1.4.-; EC 3.1.4.35;
MeSH Related Number : cyclic nucleotide phosphodiesterases, type 6, beta subunit; cyclic nucleotide phosphodiesterases, type 6, gamma subunit; cyclic nucleotide phosphodiesterases, type 6, alpha subunit; cyclic nucleotide phosphodiesterases, type 6, delta subunit; EC 3.1.4.17; EC 3.1.4.35;
Registry Number MeSH : EC 3.1.4.35;
Related CAS MeSH : EC 3.1.4.35 (Cyclic nucleotide phosphodiesterases, type 6, beta subunit); EC 3.1.4.- (Cyclic nucleotide phosphodiesterases, type 6, gamma subunit); EC 3.1.4.35 (Cyclic nucleotide phosphodiesterases, type 6, alpha subunit); EC 3.1.4.- (Cyclic nucleotide phosphodiesterases, type 6, delta subunit);
Is substance : O;
UNII : EC 3.1.4.35;
Origin ID : D054707;
UMLS CUI : C0964364;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
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A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC
GMP. It is found predominantly in the outer segment PHOTORECEPTOR CELLS of the RETINA.
It is comprised of two catalytic subunits, referred to as alpha and beta, that form
a dimer. In addition two regulatory subunits, referred to as gamma and delta, modulate
the activity and localization of the enzyme.
