dual specificity phosphatase 2

Preferred Label : dual specificity phosphatase 2;

MeSH definition : A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for EXTRACELLULAR SIGNAL-REGULATED MAP KINASES and is primarily localized to the CELL NUCLEUS.;

MeSH synonym : phosphatase, pac-1; pac-1 phosphatase; pac 1 phosphatase; pac1 phosphatase; phosphatase, pac1;

MeSH Related Number : EC 3.1.3.18;

Registry Number MeSH : EC 3.1.3.48;

Is substance : O;

UNII : EC 3.1.3.48;

Details

Origin ID

D054641;

UMLS CUI

C0251982;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cyclin-Dependent Kinase Inhibitor 3 [NCIt concept]
- Dual Specificity Protein Phosphatase 1 [NCIt concept]
- Dual Specificity Protein Phosphatase 3 [NCIt concept]
- Eyes Absent Homolog 1 [NCIt concept]
- Low Molecular Weight Phosphotyrosine Protein Phosphatase [NCIt concept]
- M-Phase Inducer Phosphatase 1 [NCIt concept]
- dual specificity phosphatase 2 [HGNC gene]
Record concept(s)
- dual specificity phosphatase 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- DUSP2 protein, human [MeSH Supplementary Concept]
- Dusp2 protein, mouse [MeSH Supplementary Concept]
- Dusp2 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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